Open Journal Systems

An empirical study on evaluation of prescribing pattern in antiepileptic therapy in pediatric patients at a tertiary care hospital

Pratibha Yadav




Over 10 million children worldwide are believed to have epilepsy. Antiepileptic drug therapy is a mainstay of treatment for most pediatric patient with epilepsy. The present study was undertaken to get an overview of the current trends in prescribing patterns of anti-epileptic drugs (AEDs) in the treatment of epilepsy in pediatrics department.


A prospective observational study was conducted in 350 beds hospital over a period of 3 months. 40 pediatric patients with confirmed seizure diagnosis and on AED therapy were enrolled from outpatient and inpatient department. All the relevant data was analyzed with the help of hospital protocol, Medscape, Micromedex, Guidelines for Diagnosis and Management of Childhood Epilepsy. Results were expressed as counts and percentages.


The analysis of the results revealed that there were 16 (40%) male patients and 24 (60%)female patients, The most prescribed drug was levetiracetam  12 (30%).In this study, the majority of the populations prescribed or treated by using the single drug therapy (97.5%) as compared to that of multiple drug therapy (2.5%).


For the acute management of seizures, mono therapy was found to be the most preferred choice of treatment and in this, levetiracetam was the preferred drug of physician’s choice.


Prescribing pattern, Hospital Protocol, Monotherapy, Epilepsy, Pediatric


Thasni K, Abdurahiman P, Assessment of prescription pattern and quality of life in patients with epilepsy: A tertiary care hospital based prospective study October 2017 ISSN: 2454-9142. World journal of pharmacy and pharmaceutical sciences ISSN 2278 – 43^57.

Sebastian J, Mathew F et al. Assessment of prescribing pattern of antiepileptic in paediatric in-patients of a tertiary care hospital doi: 10.13040/ijpsr.0975-8232.10(3).1319-24.

Thampi J, Ramanathan R. A Prospective Study on Prescribing Pattern of Anti-Epileptic Drugs in Pediatric Patients; Journal of Pharmaceutical Research & Clinical Practice, Oct-Dec 2016; 6(4):28-33 ISSN: 2231-4237.

Shaik R, Akhil A Study of anti-epileptic therapy in pediatric patients in a secondary care hospital 2052-2062 ISSN 2278 – 4357.

Eswari PVSN, kumar P An observational study on prescribing pattern of anti epileptic drugs in pediatric patients at a tertiary care hospital ISSN 2455-3301.

Guidelines for Diagnosis and Management of Childhood Epilepsy 2014 Expert Committee on Pediatric Epilepsy, Indian Academy of Pediatrics.

Maity N and Niveditha G Trends in Utilization of Antiepileptic Drugs Among Pediatric Patients in a Tertiary Care Hospital 2011 Current Neurobiology 2011; 2 (2): 117-123.

Akhila A. Lekshmi, A. Anjana, Sajila Mary Emmanuel Evaluation of Prescribing Pattern of Antiepileptic Drugs and Assessment of Quality of Life of Epileptic Patients and the Knowledge of Their Care Givers Journal of Applied Pharmaceutical Science Vol. 7 (10), pp. 152-156, October, 2017 ISSN 2231-3354.

Dave HH, Trivedi NA. Drug utilization pattern of antiepileptic agents among pediatric epilepsy at tertiary care teaching hospital of Gujarat: a cross sectional study IJBCP International Journal of Basic & Clinical Pharmacology ISSN: 2279-0780.

Full Text: PDF

Article Level Metrics


  • There are currently no refbacks.