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Trends in the use of Guideline Recommended Medications in Patients with Acute Myocardial Infarction in an Indian Population.

Asma Iqbal Ahmed Khan




The objective was to study the temporal trends used in the prescription following guidelines recommended in the treatment of ACS/AMI in an Indian population in a tertiary care hospital in South India.


It was a retrospective observational study that included 150 cases collected from the Medical Records Department of the hospital. The patient files were studied and the relevant data was collected. Using the AHA/ACCA guidelines for the treatment of AMI and ACS, the prescription results were compared and the results were noted.


Under treatment of cardiovascular disease is one of the leading causes of not only death but also increased hospitalization as well as worsening of the patient’s condition and reduction in the years of life of the patient. Guidelines were put in place in order to help curb this problem of under treatment with better outcome. The study comprised of 150 patients of varying age groups who were all above 18 years of age. Dual antiplatelet therapy (95.4%), Beta blockers (71.6%), ACEIs (33.2%), ARBs (9.8%), anticoagulants (86.2%) Statins (88.2%) and CCBs (14.4%) used.


Adherence to the guidelines has helped to reduce the mortality rates in patients with acute myocardial infarction.


Acute Myocardial Infarction, Prescribing Pattern, AHA/ACC Therapy Guidelines.


The changing patterns of cardiovascular diseases and their risk factors in the states of India: the Global Burden of Disease Study 1990–2016 Lancet Glob Health 2018; 6: e1339–51

Hu J ,Xie Y, Shu Z ,Yang W, Zhan S(2015) Trends in the Use of Guideline-Recommended Medications and In-Hospital Mortality of Patients with Acute MyocardialInfarctionin a Chinese Population. PLoSONE10(2): e0118777.doi:10.1371/journal. pone.0118777

DosedelM, HendrychovaT, MalyJ, KubenaA, BymaS and VlcekJ Prescription Of Evidence-Based Medicine Drugs By General Practitioners To Patients After Myocardial Infarction: Outcomes From The Czech Republic. Acta Poloniae Pharmaceutica ñ Drug Research, Vol. 71 No. 1 pp. 189ñ195, 2014 ISSN 0001-6837 Polish Pharmaceutical Society

Hall M, Bebb OJ , Dondo TB, Yan AT, Goodman SG, Bueno H, Chew DP, Brieger D,Batin PD,Farkouh MV,Hemingway H, Timmis A, Fox KA, Gale CP, Guideline-indicated treatments and diagnostics, GRACE risk score, and survival for non-ST elevation myocardial infarction, European Heart Journal, Volume 39, Issue 42, 07 November 2018, Pages 3798–3806,

Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE., Jr ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction. J Am Coll Cardiol. 2007;50: el—157.[PubMed]

Hammer Y, Iakobishvili Z, Hasdai D, Goldenberg I, Shlomo N, Einhorn M, et al. Guideline-Recommended Therapies and Clinical Outcomes According to the Risk for Recurrent Cardiovascular Events After an Acute Coronary Syndrome DOI: 10.1161/JAHA.118.009885

Rathod PS, Kumar TP, Patil, Lohar RP, Patil AW Prescription pattern in indoor patients of cardiovascular diseases: a descriptive study in a tertiary care hospital attached to a government medical college DOI:

Thomas BR, Catherin TJ, Sabu N, Lekshmi ES, Baby N, Menaka K, Sivakumar T Prescribing Pattern of Cardiovascular Drugs - A Prospective Observational Study Indian Journal of Pharmacy Practice, Vol 10, Issue 4, Oct-Dec, 2017 DOI: 10.5530/ijopp.10.4.58

Sneha KLK, Male A, Surendra VS, TripathyS Drug Utilisation & Prescription Pattern Analysis Study In Myocardial Infarction Patients At Tertiary Care Hospital In Krishna District, Andhra-Pradesh, India International Journal of Advanced Pharmaceutical Sciences, Volume 1, Issue 02, Page 136-142 ISSN:2456-8147

Ahamed J, Ali A, JangirR.K, GehlotA,, Vyas A. An observational study of prescription patterns of drugs used in acute myocardial infarction in Western Rajasthan DOI: 10.18231/2393-9087.2019.0001

Joseph L, Francis B and Suresha BS. Astudy on prescribing pattern of myocardial infarction in tertiary care hospital DOI: 10.20959/wjpps20185-11549

Amaravadi D, Laxmapuram S, Sabavat S, Bakshi V, Boggula N A study on prescription pattern of cardiovascular drugs in inpatient department at a tertiary care centre International Journal of Research in Pharmacy and Science 2018, 8 (2);27-32

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